The area was served by ferry service across the Ohio River until the completion of the John A. Roebling Suspension Bridge (prototype of the famous Brooklyn Bridge) in 1866, whereupon land values in the areas near the river quadrupled overnight.

Beginning in the 1970s, many factors combined to create major growth. The proximity to Cincinnati, the completion of I-75, the nexus of rail service and river traffic, creation of several industrial parks, and the growth of Cincinnati/Northern Kentucky International Airport (located near Hebron in northeastern Boone County near the Kenton County line) drew many industries into the area. Its geographically central location (within 800 miles of 80% of the US population) makes it ideal for distribution centers, and those shipping all over the country.